ChemSABRE

ALTORIS, has developed and customized a number of solutions for life sciences informatics. We form strong partnership with our users, and it is with their guidance that most our products are perfected. We keep collegial collaborations with other software companies and strive to integrate our products with other best in class complementary applications. ChemAPPS is Altoris' web store for chemical information management.

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ChemSABRE

A unique software tool for Substitutent Analysis of Bioisosteric Replacements and Enumeration. The program creates two way tables for substituents. The cells can be colored by a selected property (Heatmaps) or selected data can be graphed.From the table, the program can enumerate all possible combinations that are missing in the dataset (Hole enumeration).

CHEMSABRE comes with a database of fragment pairs that have been reported in the literature to be bioisosteric replacements. In addition, computed bioisosteric pairs that can be selected based on weighing the contribution of steric electronic or entropic properties.

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ChemSABRE allows you to Build R-group vs R-group tables with heat maps and other analytical tools; Plot R-group vs R-group properties; Enumerate missing combinations of substituents; Select bioisosteres replacements based on steric, entropic or electronic criteria

For licensing terms, to request an online demo, discuss customization or integration please contact us.