We have put together some videos and documents to show you how to use our different products. These are meant for training and not marketing. We have also placed here some Application Notes that give you an idea of how the products can be used.
INTRODUCTION. Are you still using Excel to keep your biologics sequences and data? A brief video shows you how to make your life easier, and extract more from your peptide SAR with SARvision|Biologics. Click Here
INTRODUCTION. Notes on how to manage the Residue Tables used by SARvision|Biologics. A discussion of those two critical files. Download the PDF here.
DATA VIEWS. Sequence and data in a single spreadsheet. Here is a simple document to learn the basics about coloring and other useful features.
DATA VIEWS. Logo and Bar Plots can be great tools to analyze trends in your SAR for peptides or phenotypic characteization of your antibodies. You can learn how to use them in this short document.
DATA ANALYTICS. Invariant maps show which residues have been tried at each position in the sequence alignment and how many times. Learn more here.
DATA ANALYTICS. Mutation Cliffs are set up to identify pairs of sequences that differ only at a position and organize them by one of the mutations and sequence position and correlated them to phenotyic changes. Here is how we implemented them.
PROTEIN WORK. If you are working with Protein therapeutics, including antibodies, you may want to create profiles that automatically align your sequences. Download instructions.
APPLICATION NOTE SARvision|Biologics is very useful for protein engineering, including Antibody Design. Here is a simple Application Note that to facilitate relating sequences to data in antibody design.
PUBLICATIONS. The original paper describing SARvision|Biologics can be found in J Chem. Inf. Model can be found here.
PUBLICATIONS. The short note “Sequence-activity relationship analysis for peptide optimization using machine learning techniques” has been published as part of the Proceedings of the 35th European Peptide Symposium, Patrick B. Timmons, Chandralal M. Hewage, Michal Lebl (Editors), European Peptide Society & PSP, 2018 You can find it here.
INTRODUCTION. If you need help getting started with SARvision|SM, these simple instructions may help you out.
INTRODUCTION. Organization of chemical information according to functional groups, scaffolds or other chemotypes provides a superior means to identify trends in your data. SARvision|SM has powerful automated scaffold perception algorithms that make your report generation and data assembly easier. Click Here In Japanese? Click Here
INTRODUCTION. Would you like to apply machine learning techniques to speed up your small molecule discovery? Here are the first steps you need to take with AMEDEO in the SARvision|SM environment.
DATA VIEWS. A simple document that takes you through the steps to create an R-group table, can be found here. You may want to follow it up with AMEDEO or ChemSABRE both excellent tools to extend your R-group analytics capabilities.
DATA VIEWS. Do you want to build an R-group table easily? Check this video that will take you through the creation of R-group Tables.
DATA VIEWS. Matched Molecular Pairs, that is molecules that differ in just a single functional group can be identified using SARvision|SM Click Here . Equally interesting is the analysis of pairs of molecules that differ in their core, or central scaffold, but where all pendent groups are the same. This is the idea behind scaffold hopping. Here you can watch a short video to learn more about it. Click Here We have simplified the view of the Match Molecular Pairs and a description of the update can be found here.
LIBRARY DESIGN. If you have to create chemical libraries for screening or acquire new catalogs from vendors, SARvision|SM provides you with unique tools to add new chemotypes to your screening, not just more molecules. Here is a document that shows some of the capabilities for library design.
GRAPHS. Nice graphs are useful to identify trends in your SAR. SARvision|SM provides many simple graphs most commonly used by researchers in drug discovery without making it too cumbersome to use. Simple but not too simple, fully integrated with the different table views and the scaffold and filter views. Click Here
INTEGRATION. SARvision can be integrated with CDD Vault a cloud based informatics solution widely used in the pharmaceutical and biotech industry. SARvision adds its powerful analytics tools and CDD Vault provides the cloud based solution for collaborative work. You can watch a short video that shows how easy it is to have the two applications share data, or a brief docment.
FEATURE. You can copy and paste from a variety of sources. Would you like to insert in your files a molecule you saw in a publication? Chemical images from pdfs or websites can be brought into SARvision|SM and edited, learn how to do it in this short video. After that you can take a look at some general advice on how to place your tables into PowerPoint or Word when single click exporting does not provide the needed flexibility.
APPLICATION NOTE. Large libraries of even hundreds of thousands of compounds can be analyzed with SARvision|SM. This is a simple analysis of ChemBank that illustrates some basic aspects of library analysis for design. Click Here
Announcements and Presentations
Here are some of the latest presentations we made. An overview of our product line can be found here together with some of our presentations at different events.
Poster presented at Drug Discovery Chemistry on how SARvision|SM can help in library design. Click Here
Poster presented at the 12th Peptide Therapeutics Symposia that describes how to do Exploratory Data Analysis for peptides. Click Here
Poster introducing the use of machine learning and artificial intelligence in the discovery of new biologics, peptides and proteins. Click Here
A few slides that offer a short description of our product line. Click Here