https://www.chemapps.com/home daily 1.0 2026-07-23 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1609977474795-Z1AD29NA8JCYL839395W/product_svsm_icon.jpg Home https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1609977487252-QAKUQ8HA7C476G844D8I/product_amadeo_icon.jpg Home https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1609977474816-8OU0BWZR1U9ZP496FQ41/CDDV.png Home https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1619586542674-2XCAYUK2U18XZ0GFJI6B/Patcore_newLogo.PNG Home https://www.chemapps.com/about-us daily 0.75 2021-04-20 https://www.chemapps.com/sarvision-sm daily 0.75 2021-05-03 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1620082987264-FKH1NIRWRRCVIM0MDQOT/Patcore_newLogo.PNG SARvision|SM - Is our exclusive distributor for Japan. https://www.chemapps.com/amadeo daily 0.75 2021-02-06 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1609977494675-RWXESZ1MIRV1FZOBDNON/patcore-300x89.png Amadeo - Is our exclusive distributor for Japan. https://www.chemapps.com/contact-us daily 0.75 2021-01-29 https://www.chemapps.com/work daily 0.75 2021-03-26 https://www.chemapps.com/amedeo daily 0.75 2021-05-03 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1620083067366-K76WDYVRVL39KM8DXTSM/Patcore_newLogo.PNG Amedeo - Is our exclusive distributor for Japan. https://www.chemapps.com/logos daily 0.75 2021-05-06 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/c28ccd51-bcaa-4676-9f1f-7f31566be09e/BrowserLogo.JPG Logos https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/58a90830-5664-4d2d-a793-fa7f329232e9/ChemApps.PNG Logos https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/568d77bd-4afd-4f02-b568-3434535fa861/SVSM_logo.jpg Logos https://www.chemapps.com/find-molecules daily 0.75 2025-07-18 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1626742772885-E85ZN4IYAA1UD5EPRQHQ/BuildingBlockLogo.PNG BUY MOLECULES - Make it stand out Contact us for further information. https://www.chemapps.com/resources daily 0.75 2026-07-23 https://www.chemapps.com/resources/svsm-cddvault monthly 0.5 2022-04-06 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1618017327662-OMC5FOQXWA3AZGTD6INA/CDD_SM1.PNG Resources - Analyzing Molecules from CDDVault https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1618017350349-VZJ2ULZBKXTQFSWZPWMM/CDD_SM2.PNG Resources - Analyzing Molecules from CDDVault https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1618020706623-GG77NKVDNNPLY1ESWZCR/CDD_SM3.PNG Resources - Analyzing Molecules from CDDVault https://www.chemapps.com/resources/protacs monthly 0.5 2022-04-06 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/296d6f84-03ec-47b1-88e8-a8327fb97446/PROTAC.PNG Resources - Analysing PROTAC Structure-Activity Relationships - Make it stand out Performing SAR analysis on bi-ligands such as PRTOACS requires tools that can identify the linker and break the molecule into its constituent parts. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/39400899-f101-49b6-a97b-2e35c82b39b5/OpenPROTAC_BCR-ABL.PNG Resources - Analysing PROTAC Structure-Activity Relationships - Make it stand out Molecules in SDF or smiles format can be easily imported into SARvision|SM (file->import molecles : loads SDF, Smiles). A set of molecules designed to degrade BCR-ABL can be loaded for study (download here). We are using a set obtained from PROTAC DB: Nucleic Acids Research, 2020. Doi: 10.1093/nar/gkaa807 for this example. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/ba75bdad-f0a0-485e-bf25-766656fa44e4/PROTAC_SAR_BUTTON.PNG Resources - Analysing PROTAC Structure-Activity Relationships - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/deb36329-b4e4-4d01-b119-d85e998f8048/PROTAC_RGROUP.PNG Resources - Analysing PROTAC Structure-Activity Relationships - Make it stand out The R-Group table breaks the PROTAC molecules into the constituent parts and places these into R1, R2 and Linker columns. This table can be sorted, heat-mapped and filtered to facilitate SAR analysis. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/ea6d2430-2f9c-4073-81d1-a3a338970905/PROTAC_MOLECULAR_PAIR.PNG Resources - Analysing PROTAC Structure-Activity Relationships - Make it stand out PROTACS are broken into molecular pairs on each row based on changes in only one of the ligands or the linker. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/c843bd03-f251-479b-a001-23af909003be/PROTAC_PROPERTIES.PNG Resources - Analysing PROTAC Structure-Activity Relationships - Make it stand out A number of properties can be calculated for each PROTAC, each ligand in the PROTAC molecule and for the linker. https://www.chemapps.com/resources/find-molecules monthly 0.5 2021-05-06 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/84837bf7-4368-4bc2-b96f-3b5ef054c9b1/MoleculeFinder_th.png Resources - Finding Molecules Online The CHEMAPPS search page shows results for substructure searches of vendor and other online molecules. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/41869236-951e-4f39-8c97-0a00181b8e70/MoleculeFinder_Search.PNG Resources - Finding Molecules Online The CHEMAPPS main search page where the user can search libraries of molecules by chemical type, substructure and application. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/6c874c51-35ec-4310-a514-1778d3f8ad50/MoleculeFinder_PopScaffolds.PNG Resources - Finding Molecules Online Each scaffold is grouped by chemical type and can be clicked to perform a search against a library of molecules. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/81d14aa0-a0c9-4afa-b6c6-cf427bb1b05a/MoleculeFinder_Results.PNG Resources - Finding Molecules Online Search page showing the selected scaffold (top), child scaffold families (middle) and molecule hits (bottom). Exact substructure matches are highlighted with blue squares. Below each molecule descriptive data is display such as the cas# in this case. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/ef90dcad-b01b-4b43-a2e0-2881de062d57/MoleculeFinder_Cart.PNG Resources - Finding Molecules Online The cart contains collections of molecules created by the user. These display some relevant chemical information. https://www.chemapps.com/resources/hts-analysis monthly 0.5 2021-04-30 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616912921509-25EPOQFJ9YGZGRUOKAHI/tree_thumb.PNG Resources - Analyzing High Throughput Data Using Scaffold Trees and Data Grids A hierarchical scaffold tree intuitively organizes molecules based on structure. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616913984631-C32MBBN3KQUVHXB8HLUI/tree_2.PNG Resources - Analyzing High Throughput Data Using Scaffold Trees and Data Grids A molecular grid of molecules displaying heat-mapped HTS data. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616961982955-DNCTX4Y774TI31JFW5ZV/tree_3.PNG Resources - Analyzing High Throughput Data Using Scaffold Trees and Data Grids A molecule grid of heat-mapped HTS data filter by scaffold structure or chemotype. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616962057583-M4MKMW3TALJWITXN4NWM/tree_4.PNG Resources - Analyzing High Throughput Data Using Scaffold Trees and Data Grids HTS or activity data can be mapped onto the hierarchical scaffold tree to help isolate active molecules. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616965903692-C2TRQ7PMNOYSJRD5BEVM/tree_5.PNG Resources - Analyzing High Throughput Data Using Scaffold Trees and Data Grids https://www.chemapps.com/resources/data-grid monthly 0.5 2021-04-30 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616738892080-OI3IVGQ8TQBCMQF37LS8/DataGrid_thumb.PNG Resources - Molecule Data Grid A Molecule data grid is a nice compact way to show high density data. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616738400573-1255E92UAPTZR39YY1BT/DataGrid_1.PNG Resources - Molecule Data Grid A molecular data grid displays molecules and data in a nice compact form. https://www.chemapps.com/resources/sabre monthly 0.5 2021-04-30 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616734043105-I0HQYFDTCSBJN7KK424Y/SABRE_thumb.PNG Resources - Two-Way R-Group Tables A two-way R-Group table highlights key features in R-Group space. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616735715451-6WSB3X5RSHWI9VCB8921/SABRE_1.PNG Resources - Two-Way R-Group Tables There are multiple two-way tables that can be built for a molecule set. Each represents a slice through N-dimensional R-Group space defined by a scaffold core. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616735658145-9KKKKBFIHAO8YOT2PG37/SABRE2.PNG Resources - Two-Way R-Group Tables Under the main menu are a series of dialogues that will build custom formatted two-way tables for SAR analysis. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616735738144-T36834KCNCI7HB8WINWS/SABRE_3.PNG Resources - Two-Way R-Group Tables The population of molecules in the two-way table can be filtered at any R-position to study only those with R-Groups that are relevant to the current analysis. https://www.chemapps.com/resources/rgroup-table monthly 0.5 2021-04-30 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616722771851-O1T3CDD6MLOGFKUTYDZM/RT_1.PNG Resources - R-Group Tables R-Group tables are built on demand by double clicking on any scaffold. https://www.chemapps.com/resources/molecular-pairs monthly 0.5 2021-04-30 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616723708897-XUV8P40I2BYXCKZ38A6A/mp_thumb.PNG Resources - Scaffold Centered Molecular Pairs Molecular pairs are pairs of molecules that differ at only a single position. Isolating structural changes in this way useful to study Structure Activity Relationships. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616630790613-5LKKN3D4J9FJMF15NF0X/MP_2.PNG Resources - Scaffold Centered Molecular Pairs SARvision builds molecular pair tables centered on specific scaffolds. Pairs can be easily filtered by R-position to facilitate analysis. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616630988837-XUVC06NGAQVIS0K9Q4BU/MP_3.PNG Resources - Scaffold Centered Molecular Pairs Comparing scaffold cores or core-hopping is easily performed by using folders in the scaffold tree. https://www.chemapps.com/resources/molecule-spreadsheets monthly 0.5 2021-05-06 https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616689174881-3938T0ZRBU7FHRPZ26L0/MS_1.PNG Resources - Molecule Spreadsheets A typical molecule spreadsheet. Right click on row headers, spreadsheet header tab, column header and cells to get context menus to modify objects. Click on any data cell to modify or add data. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616707300620-R9DA3KQT385JMCUEB8PG/MS_2.PNG Resources - Molecule Spreadsheets Molecular spreadsheets can be sorted, edited, heat-mapped and cells formatted to help identify trends in biological assay data. Under Data Table tab (right click) export to Excel/Word. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1620250975524-AABMA200OUF99MET8YP5/MS_3.PNG Resources - Molecule Spreadsheets Molecules cluster in related series based on scaffold substructure. Draw a scaffold and double click on it to filter, color code and align molecules to the selected scaffold for easy analysis. https://images.squarespace-cdn.com/content/v1/5ff64e7d2c86173b0bf31129/1616708252777-G1W4BWW4DCLPQZDB79CE/MS_4.PNG Resources - Molecule Spreadsheets Filter data by scaffold substructure and/or data ranges to see only relevant molecules in the spreadsheet.